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What's New about Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?  
2023/11/01
New Year's Holidays(December 29th - January 3rd)
Our office will be closed for the New Year's Holidays from December 29th to January 3rd.
We are sorry for your inconvenience during this period.
Thank you for your kind support of this year and have a great new year.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2023/07/18
Summer holidays(Aug. 11-15)

Our office will be closed for summer holidays from August 11th to 15th.
We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2023/05/31
Announcement of suspended Product

We regret to inform you that product KDT-010E Dityrosine(DT) ELISA is no longer available because we have suspended manufacturing this ELISA.
We apologize for any inconvenience this may cause and want to assure you that we will continue to offer other high-quality products to meet your needs.
Thank you for your continued support and understanding.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2023/04/03
Public holidays (Apr.29-May.7)

Our office will be closed for public holidays from April 29th to May 7th.
We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2022/11/01
NOTICE:

Our office will be closed for New Year's Holidays from December 30th, 2022 to January 3rd, 2023.
We are sorry for your inconvenience during this period.
Thank you for your kind support of this year and have a great new year.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2022/07/15
Summer holidays(Aug.11-Aug14.)

Our office will be closed from August 11th to August 14th due to the summer holidays.
We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2022/04/01
Public holidays(Apr.29-May.5)

Our office will be closed from Apirl 29th to May 5th due to the public holidays.
We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2022/03/18
Notice of the server recover

There is a problem with mail server and our website From 11:50PM on Wed, March16,2022 to 8:00AM on Fri, March 18,2022.
We apologize for your inconvenience during this period.
We operate business as usual.

What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2021/11/01
NOTICE:

Our office will be closed for New Year's Holidays from December 30th, 2021 to January 3rd, 2022.
We are sorry for your inconvenience during this period.
Thank you for your kind support of this year and have a great new year.

What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2021/10/01
NOTICE:

The government has lifted the state of emergency, Our office have resumed our business from 1st October.

Business hours: 9AM-5PM
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2021/09/13
NOTICE:

The government announced the state of emergency utill the end of September.
Our office temporary change the business hours.

Business hours: 10AM-4PM

We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2021/07/27
NOTICE:

Our office will be closed for Summer holidays from August 12th to 15th.
We are sorry for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2021/04/09
Public holidays(Apr.29-May.5)

Our office will be closed from Apirl 29th to May 5th due to the public holidays.
We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2020/12/04
NOTICE:

Our office will be closed for New Year's holidays from December 28th, 2020 to January 3rd, 2021.
We are sorry for your inconvenience during this period.
Thank you for your kind support of this year and have a great new year.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2020/04/28
NOTICE:

Our office will be closed from May 2nd to May 6th due to eh Golden Week holidays.
We apologize for your inconvenience during this period.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2019/08/08
NOTICE:

We will have summer holidays from August 10 to 18.
Thank you very much for your understanding.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2019/06/21
EXHIBITION:

We will attend 71st AACC Annual Scientific Meeting & Clinical Lab Expo (August 4-6 Anaheim) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2019/02/19
EXHIBITION:

Have attended Experimental Biology: EB2019 (April 6-9, Orlando, FL) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2018/09/10
EXHIBITION:

Have attended the Society for Redox Biology and Medicine's 25th Annual Conference (SfRBM 2018: Nov.14-17 Chicago) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2018/07/05
EXHIBITION:

Have attended AACC2018 (Jul 29- Aug 2 Chicago) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2018/07/02
[ IMPORTANT NOTICE ]
Genox has moved to California.
New Address: 21151 S. Western Ave.,
Suite 103, Torrance, CA 90501
Phone: 310-755-6554
Tech support:biotech@jaica.com or FAX (+81-538-49-1267: Japan)
Purchase order:web order form
The Baltimore office has been closed at the end of August.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/08/30
EXHIBITION:

Have attended The 11th Congress of the Pacific Society for Reproductive Medicine:
PSRM2017 (October 14-15, Osaka, Japan) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/07/18
EXHIBITION:

Have attended JASIS Life Science Innovation 2017 (September 6-8, Makuhari, Japan)
and have made a presentation about oxidative stress markers.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/07/05
EXHIBITION:

Have attended 44th Annual meeting of the Japanese Society of Toxicology (July 10-12, Yokohama, Japan) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/06/14
CFE-010 Iron Assay kit:

Have updated technical information and the list of reference papers.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/05/16
EXHIBITION:

Have attended 17th Scientific meeting of the Japanese Society of Anti-Aging edicine (JAAM 2017) (June 02-04, Tokyo, Japan) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/05/08
EXHIBITION:

Have attended 22nd International Food Ingredients and Additives Exhibition (ifia 2017) (May 24-26, Tokyo, Japan) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2017/04/12
EXHIBITION:

Have attended The 60th Annual Meeting of The Japan Diabetes Society (JDS 60) (May 18-20, Nagoya, Japan) as an exhibitor.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2016/12/19
INFORMATION:
Have updated Oxidative stress marker Selection guide.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2016/08/26
New publications about protein oxidation marker Dityrosine:
Hattori Y, et. al: Catalytic ferrous iron in amniotic fluid as a predictive marker of human maternal-fetal disorders.
J Clin Biochem Nutr 56(1),p57-63(2015) doi: 10.3164/jcbn.14-82

Dominik Levigne, et. al.: NADPH oxidase 4 deficiency leads to impaired wound repair and reduced dityrosine-crosslinking, but does not affect myofibroblast formation.
Free Radical Biology and Medicine 96, p374-384(2016) doi: 10.1016/j.freeradbiomed.2016.04.194
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2016/04/01
[ New publication ]
Pavel Rossner Jr.,Hilmi Orhan, Gudrun Koppen, Kazuo Sakai, Regina M. Santella, Antonin Ambroz, Andrea Rossnerova, Radim J. Sram,Miroslav Ciganek, Jiri Neca, Ege Arzuk, Neliye Mutlu, Marcus S. Cooke:
Urinary 8-oxo-7,8-dihydro-2��-deoxyguanosine analysis by an improved ELISA: An inter-laboratory comparison study.
Free Radical Biology and Medicine 95, p169-179(2016)
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2016/01/14
COLLABORATION: Partnership program 2016 is open.
We welcome your proposal on oxidative stress research, development and evaluation of new biomarker, and commercialization of antibodies and test kits. If any questions or any requests, please feel free to contact us.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2015/12/26
Technical information:
Have updated the referene list for nitrotryptophan antibody.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2015/07/01
[ NOTICE ]
Due to the security reasons, some e-mails would be automatically rejected by our mail server.
Similarly, e-mails attached with some types of files will be automatically discarded by the system.
If your emails would be rejected or no reply in three business days, please try again by FAX (+81-538-49-1267).

For example, following emails will be rejected:
Sent from Free e-mail address such as hotmail, yahoo, 126.com, 136.com, foxmail, icloud etc.
Emails attached with some types of files such as .zip, .pdf, .jar, .xls, and .doc files.
E-mails from some gTLDs such as '.info', '.net', '.jp','.biz' and others.
  Blocked gTLDs / domains
gTLDs completely
blocked by the server
.aero .af .al .ax .az .ba .bh .bid .blue .bo .build .bw .cat .cf .cf .ci .cl .click
.club .cm .co .date .delivery .do .ec .eu .faith .ga .gq .gy .hn .host .id .ir
.ke .kh .kim .kz .la .lb .link .loan .ma .md .me .men .mg .mk .ml .mn .mobi
.ni .np .online .pe .ph .pink .pro .promo .pw .racing .red .review .ro .ru .sd
.shop .site .st .strem .su .sv .tech .tj .tk .tn .to .top .tours .tv .tz .us .ve .vip
.wang .website .win .work .ws .xyz .zm
gTLDs frequently
blocked by the server
.ae .ar .au .bd .be .biz .br .ch .cn .cz .de .dk .es .eu .fi .fr .gr .hk .hu
.in .info .it .jp .kr .li .lt .lv .my .mx .nl .no .pk .pl .pt .sa .se .sg .th
.tr .tw .ua .uk .vn .za
gTLDs partially
blocked by the server
.com .net .org

If your email address belongs to above domains, please contact us by FAX (+81-538-49-1267).
Thank you very much for your understanding.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2014/03/03
[ New publication ]
K Sakai, S Kino, A Masuda, M Takeuchi, T Ochi, J Osredkar, B Rejc, K Gersak, N Ramarathnam, Y Kato;
Determination of HEL (Hexanoyl-Lysine Adduct): A Novel Biomarker for Omega-6 PUFA Oxidation.
Lipid Hydroperoxide-Derived Modification of Biomolecules: Subcellular Biochemistry 77,p61-72(2014)
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2014/01/23
IMPORTANT:
Our web site has been receiving huge number of DDoS attacks, and is difficult to access.
If you would need products information or technical information, please contact us by FAX (+81-538-49-1267).

A mirror site (http://jaica.web.fc2.com/e/) is also available.
We are very sorry for the inconvenience.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2013/07/01
A NEW PRODUCT:
Have released anti nitrotryptophan monoclonal antibody (code. MNW-020P), which is a novel biomarker for nitrosative stress.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2013/06/20
NEW PRODUCTS:
A series of trace elements assay kits have been released.
Measuring method: Absorbance-based colorimetric assay (microplate reader)
Samples: Serum, plasma, urine, saliva, cell lysates, drinking water and extracts from tissue, plant, hair and foods.
Target Assay principle Wavelength Assay range # of tests Code Price
Fe Ferrozine 540-580 nm 5-1,000 µg/dL 100 CFE-005 US$330
Nitroso-PSAP 740-760 nm 10-1,000 µg/dL 100 CFE-010 US$330
UIBC Bathophenanthroline 540-550 nm 10-800 µg/dL 100 CBC-800 US$330
Cu 3,5-DiBr-PAESA 570-590 nm 3-400 µg/dL 100 CCU-400 US$370
Zn 5-Br-PAPS 550-580 nm 4-1,000 µg/dL 100 CZN-001 US$310
Ca Chlorophosphonazo III 680-700 nm 0.05-20 mg/dL 200 CCA-020 US$240
o-Cresolphtalein-Complexone 560-590 nm 0.2-30 mg/dL 200 CCA-030 US$240
Mg Xyridil Blue-I 660 nm 0.05-3.5 mg/dL 100 CMG-035 US$310
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2013/05/29
NOTICE:
JaICA has received ISO 17025: 2005 certification for its radioactvity testing services. ISO/IEC 17025 is the most important standard for calibration and testing laboratories, which has many commonalities with ISO 9001: 2000 standard, but is more specific in requirements for competence.
Certification Body: Japan Accreditation Board (JAB)
Certification Number: RTL03750
Standard: JIS Q 17025:2005 (ISO/IEC 17025:2005)
Scope of Certification: Radioactivity testing services (I-131, Cs-134, and Cs-137)
                                          for food products and beverages
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2012/10/01
NEW SERVICE:
We have started radioactivity testing service for foods and water samples.
Equipment: Gamma spectrometry with germanium semiconductor detector (Canberra GC4018).
Detection limit: 0.5 - 5 bq/kg for I-131, Cs-134 and Cs-137 each.
Samples: Foods(2kg) and water(2L).
Price: 15,000JPY
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2012/02/09
A NEW PRODUCT:
Have released a new protein oxidation marker Dityrosine (DT) ELISA kit.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine? Dityrosine ELISA has been just released.
2012/01/18
PUBLICATION:
Xiao-Yu Luo, Terumi Takahara, Jiangang Hou, Kengo Kawai, Toshiro Sugiyama, Kazuhiro Tsukada, Masumi Takemoto, Masao Takeuchi, Liang Zhong, Xiao-Kang Li;
Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model.
Biochem Biophys Res Commun 417,p287-293(2012)
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2011/09/18
PUBLICATIONS:
Sun J, Sugiyama A, Masuda A, Ochi T, Takeuchi T.
Expressions of protein oxidation markers, dityrosine and advanced oxidation protein products in acetaminophen-induced liver injury in rats.
J Vet Med Sci. 73(9), p1185-1190 (2011)

Sugiyama A, Sun J, Nishinohara M, Fujita Y, Masuda A, Ochi T, Takeuchi T: Expressions of lipid oxidation markers, N(��)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity in rats.
J Vet Med Sci. 73(6), p821-826 (2011)
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2011/07/01
NOTICE:
Our FAX machine can accept group 3 (G3) transmission but can't accept super G3 transmission.
If you would have problems on sending FAX to us, please check your FAX settings.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2011/03/18
PUBLICATIONS:
Kimoto Y, Sugiyama A, Nishinohara M, Asano A, Masuda A, Ochi T, Takeuchi T.
Expressions of protein oxidation markers, dityrosine and advanced oxidation protein products in Cisplatin-induced nephrotoxicity in rats.
J Vet Med Sci. 73(3), p403-407 (2011)

Sugiyama A, Fujita Y, Kobayashi T, Ryu M, Suzuki Y, Masuda A, Ochi T, Takeuchi T.
Effect of protein malnutrition on the skin epidermis of hairless mice.
J Vet Med Sci. 73(6), p831-835 (2011)
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2011/03/14
ABOUT THE EARTHQUAKE ON MARCH 11th:
About the 9.0-magnitude earthquake on March 11th, we would like to express our deepest sympathy for the victim and their family.
Fortunately, there is no damage for our office. About the troubles in nuclear power plant in Fukushima prefecture, our company is located at 400 km west from there. No increase in radiation level can be deteced at our company, nor from our products (tested by Monitor-4, SE International Inc, USA). For more information, please contact our overseas sales department (sales@jaica.com, FAX +81-538 49 1267). (Information updated on March 30th.)
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2010/05/10
Collaboration:  As one of our research activities, we organize a consortium for antioxidant assay. Our partners are:
Shizuoka university,
University of Shizuoka,
Fuji-Tokoha University,
Hamamatsu University School of Medicine and
Shizuoka Prefectual Research Institute of Agriculture and Forestry.
If you are interested in our project, please feel free to contact us at any time.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2010/04/02
Sponsorship to Techniques in Free Radical Biology: a FEBS practical course in Hungary.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2010/02/26
NOTICE: Released a new publication on antioxidant assay (PAO/PAO-SO).
Analysis of antioxidant activities in vegetable oils and fat soluble vitamins and biofactors by the PAO-SO method.
K Sakai, et.al.:D Armstrong Ed., Adv Protocol Oxidative Stress II 594, p241-250 (2010)
http://www.amazon.com/dp/1607614103/ref=mem_taf_english-books_u
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2009/12/28
NOTICE: A change in anti hexanoyl-Lys (HEL) monoclonal antibody
The clone of anti HEL monoclonal antibody (Product code: MHL-020P) will be changed from 5H4 to 5F12 after the end of March 2010. New product code will be MHL-021P. Price and content of new product are the same as those of old one. Thank you very much for your understanding.
  Old New
Product code MHL-020P MHL-021P
Clone name clone 5H4 clone 5F12
Content 20 micro gram IgG
Price 18,900 JPY
After February 2010, in case if you would need old product (MHL-020P: clone 5H4), please contact our sales department ( sales@jaica.com, FAX +81-538 49 1267).
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2008/12/15
Updated reference list for 8-OHdG ELISA kits.
Rabbit urine 8-OHdG is reported to decrease by administration of keishibukuryogan, a Chinese traditional medicine (Kampo).
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2008/11/19
[NEW PRODUCT] DNA extractor® TIS kit (1.48MB PDF) has been released from WAKO Chemicals. This kit is designed for "Highlly Sensitive 8-OHdG Check ELISA". Nuclease P1 enzyme and other related reagents are also available from WAKO Chemicals.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2008/10/23
Selection Guide for Oxidative Stress Markers.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2008/10/21
[NEW PRODUCT] Anti dityrosine (DT) monoclonal antibody. Dityrosine is one of the biomarkers specific for protein oxidation.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2008/06/27
JaICA attend European Standards Committee of Urinary (DNA) Lesion Analysis :ESCULA.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2008/02/01
[NOTICE]
Acrolein (ACR) ELISA kit will be discontinued after April 20th, 2008. As an alternative product, we recommend to use hexanoyl-Lys adduct (HEL) ELISA kit which can detect oxidized lipids in urine, serum, tissue and cultured cells.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2006/05/29
To impove the stability, the form of anti 8-OHdG monoclonal antibody (N45.1) have been changed from liquid to lyophilized powder. Product code have been also changed from MOG-100 to MOG-100P.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
2005/01/26
[NEW PRODUCT] Antioxidant Assay kit PAO (Potential Anti Oxidant assay). This kit can detect total antioxidants in serum and food samples in 5 minutes.
What's Oxidative Stress, Oxidative Injury and Anti-Aging Medicine?
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